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Resource | Fact Sheets,
Tuberculosis (TB) is the leading infectious disease killer worldwide today. It carries profound economic and social consequences. The public health crisis of multi-drug resistant TB (MDR-TB) continues. Although 49 million lives have been saved through global efforts since 2000, actions and investments fall far short of those needed to end the TB epidemic. High-level multisectoral action is needed, and action on TB can serve as a tracer for the Sustainable Development Agenda.
Resource | Publications,
This policy paper shows how countries and stakeholders can take resolute actions to promote the R&D required to successfully reach the SDG target of ending the TB epidemic by 2030. The paper concludes by recommending steps governments and other stakeholders can take at the national and international levels to create research-enabling environments and increase funding for TB research; namely, the creation of a global strategy for TB R&D and the deployment of innovative, collaborative financing mechanisms.
Resource | Publications,
This independent review, commissioned by the Community, Rights and Gender (CRG) Department at the Global Fund Secretariat, shares findings, conclusions, and recommendations for enhancing the meaningful engagement of communities in all phases of Global Fund grants, with an emphasis on grant making and grant implementation. The review synthesizes lessons learned and good practices for how communities engage meaningfully, and identifies key principles and strategic actions the Global Fund can take to ensure greater accountability between communities, Country Coordinating Mechanisms, other key stakeholders, and the Global Fund itself.
It is important to note that HIV, tuberculosis (TB), and malaria disproportionately affect certain groups as a result of social and economic inequities that persist worldwide. These groups are often criminalized and experience human rights abuses, seriously compromising their access to health services. These groups are also uniquely positioned to take action in response to disproportionate disease burden and their social and structural drivers.
Resource | Fact Sheets,
The World Health Organization (WHO) and UNICEF has issued a joint statement, urging all National TB Programmes to replace the previously used medicines for children weighing less than 25 kg with the child-friendly dispersible TB fixed-dose combinations (FDCs) at the soonest possible time. WHO and UNICEF advise against continued use of the former sub-optimally dosed FDCs or adult formulations (crushed tablets), which may lead to under- or over-dosing, unfavourable treatment outcomes, and high likelihood of contributing to the development of drug resistance.
Resource | Publications,
The report – “Antibacterial agents in clinical development – an analysis of the antibacterial clinical development pipeline, including Mycobacterium tuberculosis” – shows a serious lack of new antibiotics under development to combat the growing threat of antimicrobial resistance. Most of the drugs currently in the clinical pipeline are modifications of existing classes of antibiotics and are only short-term solutions.
The report found very few potential treatment options for those antibiotic-resistant infections identified by WHO as posing the greatest threat to health, including drug-resistant tuberculosis which kills around 250 000 people each year. In addition to multidrug-resistant tuberculosis, WHO has identified 12 classes of priority pathogens – some of them causing common infections such as pneumonia or urinary tract infections – that are increasingly resistant to existing antibiotics and urgently in need of new treatments.
Resource | Infographics,
UNAIDS calls for the elimination of TB deaths among people living with HIV and for health systems to be strengthened and services integrated to allow for a more rapid scale-up of HIV and TB programming. Countries must expand HIV prevention and treatment programmes that include regular TB screening, preventive therapy and early treatment, since they are simple, affordable and effective programmes that prevent TB deaths.
Resource | Fact Sheets,
The world’s 370 million indigenous peoples face a plethora of issues caused by displacement, dispossession, loss of livelihood, systematic racism and abuse, and lack of recognition. Further hindering an adequate response to these challenges, there is a pervasive lack of data about indigenous peoples concerning health and other key development indicators. Data that are available show a prevalence of extreme poverty and severe health disparities that include tuberculosis (TB).
Resource | Publications,
The Global Plan to End TB 2016–2020 calls for a paradigm shift in the approach to TB, demanding a scale-up of TB prevention and care services to unprecedented coverage levels. Without this paradigm shift, we cannot see the end of TB. Measuring progress towards the 90-(90)-90 targets will unveil the gaps at each stage of the TB care cascade, exposing the unacceptably high numbers of people who are being left behind and encouraging the mobilization of essential resources for countries to ensure the delivery of quality TB services.
This report is the first in a series produced by the Stop TB Partnership. The goal is to assess the status of country TB programmes in terms of the Global Plan’s 90-(90)-90 targets and to provide a baseline for monitoring progress over the next 5 years. Currently, the 30 high TB and drug-resistant TB (DR-TB) burden countries that account for almost 80% of the global burden exhibit the biggest gaps in the areas of diagnosis for TB and DR-TB, and the provision of preventive therapy (PT). Moreover, monitoring the uptake of TB services in key populations remains a challenge due to the limited availability and disaggregation of data.
Resource | Guidelines,
This document is intended for conducting training thereby the development of human resource in TB and HIV/AIDS control and prevention. TB and HIV infection control are a combination of measures aimed at minimizing the risk of transmission within populations. Infection control requires and complements implementation of core activities in TB and HIV control and overall health-systems strengthening. It should be a major part of national infection prevention and control policies because it complements such policies – in particular, those that target including airborne infections.
Resource | Tools,
According to Global TB Report 2015, worldwide, 9.6 million people are estimated to have fallen ill with TB in 2014: 5.4 million men, 3.2 million women and 1.0 million children. Globally, 12% of the 9.6 million new TB cases in 2014 were HIV-positive. It is estimated that accurate diagnosis and good reporting system children are likely to contribute 10-20% of disease burden in areas where the TB is poorly controlled. The incidence of paediatric TB provides an accurate measure of ongoing transmission within communities, which is a key indicator of control. Despite decline in death due to TB globally is still very high. In 2014, TB killed 1.5 million people (1.1 million HIV-negative and 0.4 million HIVpositive), making it one of the deadliest disease in the planet. The toll comprised 890,000 men, 480,000 women and 140,000 children.
A common misconception is that children are not severely affected by the TB epidemic and rarely develop severe forms of disease. This is not the case in TB endemic areas, where children are often present with advanced and serious disease (TB meningitis, Miliary TB).