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Resource | Publications,
This package forms part of a broader series of interventions to find and treat all people with TB, particularly those who currently face barriers to accessing TB services or completing TB treatment, and to support an enabling environment for overcoming the various legal, social and economic barriers that people affected by TB encounter. While it is acknowledged that persons deprived of liberty is a broad description that may include prisoners, this package specifically focuses on the latter and considers specific measures that may be adopted to ensure the effective realization of their right to access TB (and other) health services.
Resource | Publications,
This Step Up for TB 2020 report by the Stop TB Partnership and Médecins Sans Frontières (MSF) summarises findings from the 4th survey of national TB policies in the Step Up for TB series. This edition presents data on 37 high-burden countries (representing 77% of the global estimated TB incident cases), assessing the extent to which national policies align with international best practices based on WHO guidelines and the latest scientific research. It also reports on some of the barriers to policy adoption and implementation identified by NTPs, although it does not attempt to portray the level of implementation across all policies featured. It offers an insight into the ambitions of governments around the world regarding the care they aim to provide. These ambitions are considered in the context of countries’ global commitments and progress in implementation, as reported by WHO.
Resource | Publications,
This document provides guidance to countries on preparing and updating plans to mitigate the impact of coronavirus diseases (COVID-19) on tuberculosis (TB) services. The overall goal is to restore and accelerate TB services to meet national and global targets to end TB. It includes considerations on setting priorities and planning for interventions based on the country’s TB and COVID-19 situation, other contextual factors, and identification and mobilization of required resources.
The primary target audiences for the Information Note are National TB Programs and Principal Recipients of Global Fund grants. The document can also be used by other stakeholders interested in developing or improving their TB restorative and catch-up plans for COVID-19 and/or support national programs.
Resource | Publications,
The Global Strategy for Tuberculosis Research and Innovation will support the efforts of governments and other stakeholders to accelerate TB research and innovation, and improve equitable access to the benefits of research.
Resource | Publications,
Tuberculosis (TB) is a major yet preventable global health problem, with an estimated 10 million people developing TB and 1.5 million people dying every year worldwide, making it the leading infectious disease cause of death worldwide. One quarter of the global population is estimated to be infected with Mycobacterium tuberculosis. Treatment of TB infection, also known as TB preventive treatment (TPT), aims to prevent the development of TB disease, and is one of the critical components to achieve the ambitious targets of the WHO End TB Strategy. At the United Nations High-level Meeting on TB in 2018, countries committed to provide TPT to at least 30 million people in 2018-2022.
Resource | Publications,
TB remains the top infectious killer in the world claiming close to 4000 lives a day. Millions of people continue to fall ill with TB- a preventable and curable disease each year. The Global TB Report 2020 provides a comprehensive and up-to-date assessment of the TB epidemic, and progress in the response, at global, regional and country levels in the context of global commitments and strategies.
The report features data on disease trends and the response to the epidemic in 198 countries and territories. This includes trends in TB incidence and mortality, data on case detection and treatment results for TB, multidrug-resistant TB (MDR-TB), TB/HIV, TB prevention, universal health coverage as well as financing. Also included is an overview of pipelines for new TB diagnostics, drugs and vaccines.
Resource | Publications,
This is a summary review of progress towards global TB targets, and in implementation of the political declaration of the UN High Level Meeting on TB declaration. Overall the report shows that high-level commitments and targets have galvanized global and national progress towards ending TB, but that urgent and more ambitious investments and actions are required to put the world on track to reach targets, especially in the context of the COVID-19 pandemic.
Resource | Publications,
Tuberculosis (TB) is the world's leading infectious disease, killing around 1.5 million people each year. Despite global and national efforts to end TB and the availability of cost-effective medicines to treat and cure it, too many people continue to suffer from this old disease. In response to early warnings that COVID-19 was having a devastating impact on people affected by TB and TB programs around the world, 10 global networks quickly came together to take action.
Resource | Publications,
This framework for evaluation of new immunodiagnostic tests for the detection of TB infection aims to promote and direct research by identifying standard study designs and evaluation protocols. As such it should facilitate their standardized evaluation and accelerate adoption into global and national policy and subsequent scale-up.
The focus of this framework is on evaluation of diagnostic performance of tests for TB infection and provides guidance on study design, populations, reference standards, sample size calculation and data analysis. Additionally, it covers technical issues that should be considered when evaluating new tests for TB infection, evaluation of safety for skin tests, costs to the health system patients, preferred features and operational characteristics.
The document is intended for test manufacturers, researchers, research funders, regulators, TB programme coordinators, civil society and other stakeholders.
Resource | Publications,
The major causes of morbidity and mortality among children living with HIV in low- and middle-income countries are pneumonia (including Pneumocystis pneumonia), tuberculosis (TB), bloodstream infections, diarrhoeal disease and severe acute malnutrition. In addition, for adolescents living with HIV, adult-type opportunistic infections also occur, including cryptococcal meningitis. WHO published guidelines on the management of advanced HIV disease in 2017, promoting a package of interventions to prevent, identify and treat HIV-associated infections among people with advanced HIV disease. This publication builds on the 2017 guidelines and highlights existing WHO recommendations and implementation considerations that are relevant to the care of children and adolescents with advanced HIV disease. It is therefore not meant to be a comprehensive review of all severe comorbidities that affect children living with HIV. In addition, many of the interventions described here are also relevant for children and adolescents living with HIV who do not have advanced disease.