Global Priority List of Antibiotic-resistant Bacteria to Guide Research, Discovery, and Development of New Antibiotics. WHO. (2017)

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The World Health Organization was requested by Member States to develop a global priority pathogens list (global PPL) of antibiotic-resistant bacteria to help in prioritizing the research and development (R&D) of new and effective antibiotic treatments. To date, the selection of pathogens for R&D activities has been largely guided by small and large pharmaceutical companies according to a variety of parameters, such as perceived/unmet medical need, pressure of investors, market size, scientific discovery potential, and availability of specific technologies. Previous PPLs, issued by the Centers for Disease Control and Prevention.


Keywords: new antibiotics, treatment, drugs, antibiotic resistance

 

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Briefing Paper: Drug Dependence Treatment in China: A Policy Analysis. Tibke P. (2017)

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Drug use and supply have been a sensitive and high-priority issue for successive governments in China since at least the Opium Wars in the mid-19th century. China’s policy response to drug use relies on punishment and coercion as central components, including compulsory detoxification, detention in labour camps or so-called ‘rehabilitation’ facilities, and compulsory registration with law enforcement authorities resulting in surveillance and random interrogations. 

 

Yet, in the late-1990s, in a policy move that appeared to emphasize healthcare instead of punishment for people who inject drugs, China began implementing the world’s largest scale-up provision of opioid substitution therapy (OST) and needle and syringe programmes (NSP) – two critical harm reduction measures for preventing HIV transmission. However, the overall approach towards people who use drugs remains punitive and stigmatising in China. As drug use continues to rise and expand across a greater range of drugs (especially synthetic drugs such as methamphetamine), as well as amongst younger age groups, China requires a comprehensive system of evidence-based and humane drug treatment and harm reduction services capable of advancing the health and quality of life of individuals and communities.

 

Keywords: China, HIV, PWID, NSPs and OST, drugs, health, law

 

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Patients Helping Patients Understand Opioid Substitution Treatment. Chapman J, Fowler A, Mackenzie B, et al. (2017)

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This handbook has been written by a group of patients in British Columbia. We all have long experience with medication-assisted treatments for opioid dependence. The language about drug use is complex. The latest version of the manual that defines diseases and disorders (DSM-V) no longer refers to “dependence” and uses “addiction” instead. In this handbook, we continue to use “dependence” to refer to our experience of “needing the drug” and significant withdrawal symptoms when trying to quit or cut down on our use. Deciding to seek help is an important step in any process of recovery. You are making a wise decision to seek help now. People dependent on opioid drugs and not receiving opioid substitution treatment (OST) are many times more likely to die or be seriously harmed by problem drug use.


Keywords: HIV/AIDS, OST, testing, harm reduction, stigma

 

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Promoting Innovation and Access to Health Technologies. United Nations Secretary-General High-Level Panel on Access to Medicines. (2016)

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Whether it’s the rising price of the EpiPen, or new outbreaks of diseases, like Ebola, Zika and yellow fever, the rising costs of health technologies and the lack of new tools to tackle health problems, like antimicrobial resistance, is a problem in rich and poor countries alike. 
 
According to a High-Level Panel convened to advise the UN Secretary-General on improving access to medicines, the world must take bold new approaches to both health technology innovation and ensuring access so that all people can benefit from the medical advances that have dramatically improved the lives of millions around the world in the last century. 
 

 

Keywords: TRIPS, Antimicrobial resistance (AMR), health technology, access

 


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HIV Treatment #HLM2016AIDS. UNAIDS. (2016)

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The world has embraced the UNAIDS 90–90–90 treatment target, whereby 90% of people living with HIV know their HIV status, 90% of people who know their HIV-positive status are accessing antiretroviral treatment, and 90% of people on treatment have suppressed viral loads. By reaching the 90–90–90 treatment target by 2020, the world will be firmly on track towards ending the AIDS epidemic by 2030.

 

Keywords: HIV, treatment, HLM2016AIDS, ART, Fast-Track

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Myanmar Case Study: Increasing Access to HIV Treatment. Mburu G, Paing AZ, Myint NN, Wang B, et al. (2016)

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There has been a rapid increase in the number of people living with HIV in Myanmar over the last decade, the majority of who are eligible for treatment. Alongside this increase has been an effort by the ministry of health to rapidly scale up provision of treatment in order to reduce HIV-related illnesses and deaths.

However, Myanmar has an ambitious national strategic goal of providing ART to 106,058 people by the end of 2016. The health system in Myanmar is already stretched, and to achieve this goal, innovation in ART delivery will be required in-order to ensure that ART is provided close to communities, without compromising quality.


Keywords: HIV, ART, healthcare, CD4 count, treatment

 

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Biomedical AIDS Research. UNAIDS. (2016)

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Scientific evidence is essential for policies and programmes to advance the vision of UNAIDS of zero HIV infections, zero discrimination and zero AIDS-related deaths. New scientific information is becoming available at a rapid pace, and many of the findings are potentially important to guide future action against AIDS. To ensure this, UNAIDS has access to the latest scientific developments; a UNAIDS Scientific Expert Panel was established to advise UNAIDS on major new scientific discoveries and research evidence as well as research gaps and strategic AIDS research needs. The Scientific Expert Panel comprises more than 40 scientists from around the world with expertise in a wide range of disciplines, including epidemiology, behavioural science, virology, diagnostics, pathogenesis, immunology, treatment, prevention and cure.


Keywords: HIV, prevention, pathogenesis, diagnostics, cure, treatment

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Global Report on Access to Hepatitis C Treatment. WHO. (2016)

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This is the first-ever global report on treatment access to hepatitis C medicines. The report provides the information that countries and health authorities need to identify the appropriate HCV treatment, and procure it at affordable prices. The report uses the experience of several pioneering countries to demonstrate how barriers to treatment access can be overcome. It also provides information on the production of new hepatitis C drugs and generic versions worldwide, including where the drugs are registered, where the drugs are patented and where not, and what opportunities countries have under the license agreements that were signed by some companies as well as current pricing of all recommended DAAs, including by generic companies all over the world.

 

Keywords: HIV, hepatitis C, HCV, treatment, diagnosis, testing

 

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Progress Report 2016 - Prevent HIV, Test and Treat All. WHO (2016)

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The global HIV epidemic claimed fewer lives in 2015 than at any point in almost two decades, and fewer people became newly infected with HIV than in any year since 1991. The list of countries on the brink of eliminating new HIV infections among children keeps growing. A massive expansion of antiretroviral therapy (ART) has reduced the global number of people dying from HIV-related causes to about 1.1 million in 2015 – 45% fewer than in 2005. UNAIDS/WHO estimates show that more than 18 million people were receiving ART in mid-2016.


Keywords: HIV, Fast-Track, 90-90-90, public health, prevention, testing

 

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Combating Hepatitis B and C to Reach Elimination by 2030 - Advocacy Brief. WHO. (2016)

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In 2013, viral hepatitis was a leading cause of death worldwide (1.46 million deaths, a toll higher than that from HIV, tuberculosis or malaria, and on the increase since 1990). More than 90% of this burden is due to the sequelae of infections with the hepatitis B virus (HBV) and hepatitis C virus (HCV).

Prevention can reduce the rate of new infections, but the number of those already infected would remain high for a generation. In the absence of additional efforts, 19 million hepatitis-related deaths are anticipated from 2015 to 2030. Treatment now can prevent deaths in the short- and medium term. 


Keywords: HIV, hepatitis B and C, treatment, prevention, testing


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Highlighted publications
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Nepal-IBBS-FIDU-Kathmandu-valley-RI-2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_Get_on_the_Fast-Track_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/NEC_HIV_July-Oct-AIDSreg2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_methods_for_deriving_estimates_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_Global_AIDS_Response_Progress_Reporting_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/2015_Size_Estimation_of_Key_Affected_Populations_in_Philippines.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Assessment_of_Decentralization_of_ART_in_MMR_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS-2016-prevention-gap-report_en.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_AIDS_by_the_numbers_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_Biomedical_AIDS_research_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Implementing_comprehensive_HIV_and_STI_programmes_with_transgender_people_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/UNAIDS_cities_ending_the_aids_epidemic_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Philippines_2015_IHBSS_Factsheets.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Pakistan_IBBS_Report_Punjab_2014_0.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/WHO_Integrating_collaborative_TB_and_HIV_services_within_a_comprehensive_package_of_care_for_PWID_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/India_IBBS_report_2014-15.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/India_HSS_report_2014-15.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/The_negative_impact_of_drug_control_on_public_health_2015.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/2015_young_people_drugs_en.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Death_Penalty_for_Drug_Offences_Global_Overview_2015.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Transforming_our_world_2015_UN.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/WHO_Consolidated_on_the_use_of_antiretroviral_drugs_for_treating_and_preventing_HIV_infection_2016.pdf
http://www.aidsdatahub.org/sites/default/files/highlight-reference/document/Consolidated_Strategic_Information_Guidelines_for_HIV_in_Health_Sector_2015.pdf
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